Structure of PDB 1vzj Chain F Binding Site BS01

Receptor Information
>1vzj Chain F (length=34) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQ
Ligand information
>1vzj Chain E (length=27) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TLDEAERQWKAEFHRWSSYMVHWKNQF
Receptor-Ligand Complex Structure
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PDB1vzj The Synaptic Acetylcholinesterase Tetramer Assembles Around a Polyproline-II Helix
Resolution2.35 Å
Binding residue
(original residue number in PDB)
E7 K11 W17 M21 W24 F28
Binding residue
(residue number reindexed from 1)
E7 K11 W17 M21 W24 F28
Enzymatic activity
Enzyme Commision number 3.1.1.7: acetylcholinesterase.
External links
PDB RCSB:1vzj, PDBe:1vzj, PDBj:1vzj
PDBsum1vzj
PubMed15526038
UniProtP22303|ACES_HUMAN Acetylcholinesterase (Gene Name=ACHE)

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