Structure of PDB 1lwu Chain F Binding Site BS01

Receptor Information
>1lwu Chain F (length=317) Species: 7757 (Petromyzon marinus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTVQKILEEVRILEQIGVSHDAQIQELSEMWRVNQQFVTRLQQQLVDIRQ
TCSRPCQDTTANKISPITGKDCQQVVDNGGKDSGLYYIKPLKAKQPFLVF
CEIENGNGWTVIQHRHDGSVNFTRDWVSYREGFGYLAPTLTTEFWLGNEK
IHLLTGQQAYRLRIDLTDWENTHRYADYGHFKLTPESDEYRLFYSMYLDG
DAGNAFDGFDFGDDPQDKFYTTHLGMLFSTPERDNDKYEGSCAEQDGSGW
WMNRCHAGHLNGKYYFGGNYRKTDVEFPYDDGIIWATWHDRWYSLKMTTM
KLLPMGRDLSGHGGQQQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1lwu Chain F Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1lwu Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		D316 D318 Y320 E321 G322
Binding residue
(residue number reindexed from 1)		D234 D236 Y238 E239 G240
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007596 blood coagulation

View graph for
Biological Process
External links
PDB RCSB:1lwu, PDBe:1lwu, PDBj:1lwu
PDBsum1lwu
PubMed12162736
UniProtP04115|FIBG_PETMA Fibrinogen gamma chain (Gene Name=FGG)

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