Structure of PDB 1le5 Chain F Binding Site BS01

Receptor Information
>1le5 Chain F (length=313) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNY
VGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGVCTVTAGPKDMVVGFANL
GILHVTKKKVFETLEARMTEACIRGYNPGLLVHSDLAYLQAEGGGDRQLT
DREKEIIRQAAVQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI
YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEE
NGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDL
ETSEPKPFLYYPE
Ligand information
Receptor-Ligand Complex Structure
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PDB1le5 The X-ray crystal structure of the NF-kB p50/p65 heterodimer bound to the Interferon beta-kB site
Resolution2.75 Å
Binding residue
(original residue number in PDB)		R54 R56 S63 H64 G65
Binding residue
(residue number reindexed from 1)		R17 R19 S26 H27 G28
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1le5, PDBe:1le5, PDBj:1le5
PDBsum1le5
PubMed11970948
UniProtP25799|NFKB1_MOUSE Nuclear factor NF-kappa-B p105 subunit (Gene Name=Nfkb1)

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