Structure of PDB 1l1o Chain F Binding Site BS01

Receptor Information
>1l1o Chain F (length=171) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTNWKTLYEVKSENLGQGDKPDYFSSVATVVYLRKENCMYQACPTQDCNK
KVIDQQNGLYRCEKCDTEFPNFKYRMILSVNIADFQENQWVTCFQESAEA
ILGQNAAYLGELKDKNEQAFEEVFQNANFRSFIFRVRVKVEIKATVMDVK
PVDYREYGRRLVMSIRRSALM
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1l1o Chain F Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1l1o Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		C481 C486 C500 C503
Binding residue
(residue number reindexed from 1)		C43 C48 C62 C65
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:1l1o, PDBe:1l1o, PDBj:1l1o
PDBsum1l1o
PubMed11927569
UniProtP27694|RFA1_HUMAN Replication protein A 70 kDa DNA-binding subunit (Gene Name=RPA1)

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