Structure of PDB 1fzd Chain F Binding Site BS01

Receptor Information
>1fzd Chain F (length=197) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQ
RGSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEG
SVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNG
IYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1fzd Chain F Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1fzd Crystal structure of a recombinant alphaEC domain from human fibrinogen-420.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D772 D774 W776 E778 N779
Binding residue
(residue number reindexed from 1)		D122 D124 W126 E128 N129
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007596 blood coagulation

View graph for
Biological Process
External links
PDB RCSB:1fzd, PDBe:1fzd, PDBj:1fzd
PDBsum1fzd
PubMed9689040
UniProtP02671|FIBA_HUMAN Fibrinogen alpha chain (Gene Name=FGA)

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