Structure of PDB 1fzc Chain F Binding Site BS01

Receptor Information
>1fzc Chain F (length=301) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIH
DITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQK
RLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYAL
RVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFG
DDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNG
VYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGE
G
Ligand information
Receptor-Ligand Complex Structure
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PDB1fzc Crystal structure of fragment double-D from human fibrin with two different bound ligands.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		F295 D301 F322 Q329 K338 C339 H340 Y363 D364
Binding residue
(residue number reindexed from 1)		F199 D205 F226 Q233 K242 C243 H244 Y267 D268
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1fzc, PDBe:1fzc, PDBj:1fzc
PDBsum1fzc
PubMed9628725
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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