Structure of PDB 1fu2 Chain F Binding Site BS01

Receptor Information
>1fu2 Chain F (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
>1fu2 Chain E (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB1fu2 The first protein crystal structure determined from high-resolution X-ray powder diffraction data: a variant of T3R3 human insulin-zinc complex produced by grinding.
ResolutionN/A
Binding residue
(original residue number in PDB)
F1 N3 Q4 H5 L6 C7 V18 C19 R22 G23 F25 T27 P28 T30
Binding residue
(residue number reindexed from 1)
F1 N3 Q4 H5 L6 C7 V18 C19 R22 G23 F25 T27 P28 T30
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:1fu2, PDBe:1fu2, PDBj:1fu2
PDBsum1fu2
PubMed11092920
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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