Structure of PDB 1aot Chain F Binding Site BS01
Receptor Information
>1aot Chain F (length=106) Species:
9606
(Homo sapiens) [
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SIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW
DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLSSRL
VVPSHK
Ligand information
>1aot Chain P (length=11) [
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EPQYEEIPIYL
Receptor-Ligand Complex Structure
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PDB
1aot
The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity.
Resolution
N/A
Binding residue
(original residue number in PDB)
R14 R34 H60 Y61 K62 T74 R76 G95 L96
Binding residue
(residue number reindexed from 1)
R14 R34 H60 Y61 K62 T74 R76 G95 L96
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:1aot
,
PDBe:1aot
,
PDBj:1aot
PDBsum
1aot
PubMed
9351806
UniProt
P06241
|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)
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