Structure of PDB 8b6h Chain Ef Binding Site BS01

Receptor Information
>8b6h Chain Ef (length=188) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSAILKRAAKYKRVSSILCEGEAHLRDPFTPPPVILKPPAPRKDKKPDDI
TDFPAQKLIPLPESIPYQEGKYRPASIPMVAGFFPYNCYLQQGKVYSWCS
CGISQSGPWCDGLCNSVVTRCRPVVFNVSQSGYYKICNCKFSANAPFCNN
THRKMVRYHHQTHRGFYEIWGAALFVLGWVYMGFNYYT
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8b6h Chain Ef Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8b6h Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		C137 N138 C139 S142 C148 N149 N150 T151 H152
Binding residue
(residue number reindexed from 1)		C137 N138 C139 S142 C148 N149 N150 T151 H152
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0106034 protein maturation by [2Fe-2S] cluster transfer
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8b6h, PDBe:8b6h, PDBj:8b6h
PDBsum8b6h
PubMed36949187
UniProtI7M8P0

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