Structure of PDB 6yxx Chain EF Binding Site BS01

Receptor Information
>6yxx Chain EF (length=297) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ISFSGRQLWNSTKLLRENGNVRRSHGACVVGGASAIRRVWRDYKIRPNVV
YVPDTEPTVASWCLEDELPTCIVRCSPVEINRGLLSAELADGHAAEFPIP
ASPSVETFLGEGKPSRLTSMLVLVGLRIPSNVGTLIRAAVEMGFESVLLI
NCLDPFGEKALRASEGTVFSPQFKIFEPGSDPVSALNSIAVEHNLLPLLA
LPSQKAETAFEVAKNLHKINAMRRSQENHIGPLLILGSEAKGLRDLAGEW
SVPRKFVSVPLPNSTVESLNVSVAGSILIHAFRPAAEKHFVELEESA
Ligand information
>6yxx Chain AA (length=904) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB6yxx Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Resolution3.9 Å
Binding residue
(original residue number in PDB)
A141 E142 L143 L207 K213 E330 N333
Binding residue
(residue number reindexed from 1)
A87 E88 L89 L153 K159 E267 N270
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008173 RNA methyltransferase activity
Biological Process
GO:0006396 RNA processing

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:6yxx, PDBe:6yxx, PDBj:6yxx
PDBsum6yxx
PubMed32679035
UniProtC9ZWD9

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