Structure of PDB 7zux Chain ED Binding Site BS01

Receptor Information
>7zux Chain ED (length=294) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVV
RFTNKDIICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGL
LIARRTLQKLGLDETYKGVEEVEGEYELTEAVEDGPRPFKVFLDIGLQRT
TTGARVFGALKGASDGGLYVPHSENRFPGWDFETEEIDPELLRSYIFGGH
VSQYMEELADDDEERFSELFKGYLADDIDADSLEDIYTSAHEAIRADPAF
KPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ
Ligand information
>7zux Chain 4 (length=121) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguugcggccauaucuaccagaaagcaccguuucccguccgaucaacugu
aguuaagcugguaagagccugaccgaguaguguagugggugaccauacgc
gaaacucaggugcugcaaucu
<<<<<<<<<....<<<<<<<<.....<<.<<..............>>...
.>>....>>>>>>.>><<<<<<.......<<<<<..<<....>>.>>>>>
.....>>>>>>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB7zux Structural basis for clearing of ribosome collisions by the RQT complex.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		S10 S13 S14 T18 F20 R21 R22 R24 Y30 R33 R50 R54 T56 N57 K58 I61 Q63 I65 I69 G71 D72 V74 G91 T93 N94 W95 Q151 R152 T155 A157 R158 F185 H203 Y207 E210 E221 L222 T256 K258 F260 Y265 A266 E268 S269 Y272 Q274 T275 K276 L277 K279 R282 V286
Binding residue
(residue number reindexed from 1)		S7 S10 S11 T15 F17 R18 R19 R21 Y27 R30 R47 R51 T53 N54 K55 I58 Q60 I62 I66 G68 D69 V71 G88 T90 N91 W92 Q148 R149 T152 A154 R155 F182 H200 Y204 E207 E218 L219 T253 K255 F257 Y262 A263 E265 S266 Y269 Q271 T272 K273 L274 K276 R279 V283
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zux, PDBe:7zux, PDBj:7zux
PDBsum7zux
PubMed36801861
UniProtP26321|RL5_YEAST Large ribosomal subunit protein uL18 (Gene Name=RPL5)

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