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Receptor Information

>6yxx Chain ED (length=598) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MKVSSRGPIVRWALSRPTSGLVSSPSEWRCGRDLSDEEKHSGLLLRIRDI
CQPLAKNDQLPVAVVKAQPSDLQVNEVDAVGDVAALSKVVKGKWRKISRQ
KTLLIEDDARTPFSDPSKSFSPRVQSYGEYVRLTGKLPRDLPVLRFVLYR
DSYSLNSVENRLGYVLSLQPDCVFLRDQPGGSFGCITQHGVCLGVTKEIL
SHASRHYNLHPLIFEPREYFSTDKLHSLLQGARGHHHRVLLRCVEGSQDT
IRALLKKTAERGFINYFWLDRFSVGTNRFFDMAVLAARGDYLKSIGALLH
CVAESNGVHYDHFLKYLNADPSTVPGIAQTWATTAKHMRSPNWIVQLLRG
LHKYHADAECGKSSYLAELWSALPMREALRRSAAEFVWNAMASQRLLSKG
LNVVEGDVVRMGNYHLVTKDDEEKGTFKITDVVLPVPYGSVAANNCLFPH
LSPLDKKLYVEFATKHGMSFLFDEQMPSPLSNPLQFYRHLITKPVNMQVS
VIRDPNSLTSIKSDLAVMQERKLVQIGDIDYSTRVREPCVYNVSERFTEK
MEEILKTHRGPNSVVLSCYLPEDSSPFVMLREVFDLRHASFHDLYGLL

>6yxx Chain AA (length=904) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

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Receptor-Ligand Complex Structure

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Structure summary

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PDB	6yxx Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Resolution	3.9 Å
Binding residue (original residue number in PDB)	K91 K93 W94 R95 K96 R99 L103 R110 Q125 Y130 Y164 Y207 K336 R339
Binding residue (residue number reindexed from 1)	K91 K93 W94 R95 K96 R99 L103 R110 Q125 Y130 Y164 Y207 K336 R339

Enzyme Commision number

	Molecular Function
GO:0003723	RNA binding
GO:0009982	pseudouridine synthase activity
GO:0016853	isomerase activity

	Biological Process
GO:0001522	pseudouridine synthesis
GO:0009451	RNA modification

	Cellular Component
GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005762	mitochondrial large ribosomal subunit

PDB	RCSB:6yxx, PDBe:6yxx, PDBj:6yxx
PDBsum	6yxx
PubMed	32679035
UniProt	Q385G9

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Structure of PDB 6yxx Chain ED Binding Site BS01