Structure of PDB 7lhd Chain EC Binding Site BS01

Receptor Information

>7lhd Chain EC (length=132) Species: 39803 (Qubevirus durum)

AKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTV
SVSQPSRNRKNYKVQVKIQNPTACTANGSCDPSVTRQAYADVTFSFTQYS
TDEERAFVRTELAALLASPLLIDAIDQLNPAY

Ligand information

>7lhd Chain A (length=4217)

ggggacccccuuuagggggucaccucacacagcaguacuucacugaguau
aagaggacauaugccuaaauuaccgcguggucugcguuucggagccgaua
augaaauucuuaaugauuuucaggagcucugguuuccagaccucuuuauc
gaaucuuccgacacgcauccgugguacacacugaagggucguguguugaa
cgcccaccuugaugaucgucuaccuaauguaggcggucgccagguaaggc
gcacuccacaucgcgucaccguuccgauugccucuucaggccuucguccg
guaacaaccguucaguaugaucccgcagcacuaucguucuuauugaacgc
ucguguugacugggauuucgguaauggcgauagugcgaaccuugucauua
augacuuucuguuucgcaccuuugcaccuaaggaguuugauuuuucgaac
uccuuaguuccucguuauacucaggccuucuccgcguuuaaugccaagua
uggcacuaugaucggcgaagggcucgagacuauaaaauaucucgggcuuu
uacugcgcagacugcgugaggguuaccgcgcuguuaagcguggcgauuua
cgugcucuucguaggguuauccaguccuaccauaaugguaaguggaaacc
ggcuacugcugguaaucucuggcuugaauuucguuauggccuuaugccuc
ucuuuuaugacaucagagaugucauguuagacuggcagaaccgucaugau
aagauucaacgccuccuucgguuuucuguuggucacggcgaggauuacgu
ugucgaauucgacaaucuguacccugccguugcuuacuuuaaacugaaag
gggagauuacacucgaacgccgucaucgucauggcauaucuuacgcuaac
cgcgaaggauaugcuguuuucgacaacgguucccuucggccuguguccga
uuggaaggagcuugccacugcauucaucaauccgcaugaaguugcuuggg
aguuaacucccuacagcuucguuguugauugguucuugaauguuggugac
auacuugcucaacaaggucagcuauaucauaauaucgauauuguagacgg
cuuugacagacgugacauccggcucaaaucuuucaccauaaaaggugaac
gaaaugggcggccuguuaacguuucugcuagccugucugcugucgauuua
uuuuacagccgacuccauacgagcaaucuuccguucgcuacacuagaucu
ugauaccaccuuuaguucguuuaaacacguucuugauaguaucuuuuuau
uaacccaacgcguaaagcguugaaacuuugggucaauuugaucauggcaa
aauuagagacuguuacuuuagguaacaucgggaaagauggaaaacaaacu
cugguccucaauccgcgugggguaaaucccacuaacggcguugccucgcu
uucacaagcgggugcaguuccugcgcuggagaagcguguuaccguuucgg
uaucucagccuucucgcaaucguaagaacuacaagguccagguuaagauc
cagaacccgaccgcuugcacugcaaacgguucuugugacccauccguuac
ucgccaggcauaugcugacgugaccuuuucguucacgcaguauaguaccg
augaggaacgagcuuuuguucguacagagcuugcugcucugcucgcuagu
ccucugcugaucgaugcuauugaucagcugaacccagcguauugaacacu
gcucauugccggugguggcucagggucaaaacccgauccgguuauuccgg
auccaccgauugauccgccgccagggacagguaaguauaccugucccuuc
gcaauuuggucccuagaggagguuuacgagccuccuacuaagaaccgacc
guggccuaucuauaaugcuguugaacuccagccucgcgaauuugauguug
cccucaaagaucuuuugggcaauacaaaguggcgugauugggauucucgg
cuuaguuauaccacguuccgcgguugccguggcaaugguuauauugaccu
ugaugcgacuuaucuugcuacugaucaggcuaugcgugaucagaaguaug
auauucgcgagggcaagaaaccuggugcuuucgguaacauugagcgauuc
auuuaucuuaagucgauaaaugcuuauugcucucuuagcgauauugcggc
cuaucacgccgauggcgugauaguuggcuuuuggcgcgauccauccagcg
guggugccauaccguuugacuucacuaaguuugauaagacuaaauguccu
auucaagccgugauagucguuccucgugcuuaguaacuaaggaugaaaug
caugucuaagacagcaucuucgcguaacucucucagcgcacaauugcgcc
gagccgcgaacacaagaauugagguugaagguaaccucgcacuuuccauu
gccaacgauuuacuguuggccuauggucagucgccauuuaacucugaggc
ugaguguauuucauucagcccgagauucgacgggaccccggaugacuuua
ggauaaauuaucuuaaagccgagaucaugucgaaguaugacgacuucagc
cuagguauugauaccgaagcuguugccugggagaaguuccuggcagcaga
ggcugaaugugcuuuaacgaacgcucgucucuauaggccugacuacagug
aggauuucaauuucucacugggcgagucauguauacacauggcucguaga
aaaauagccaagcuaauaggagauguuccguccguugaggguauguugcg
ucacugccgauuuucuggcggugcuacaacaacgaauaaccguucguacg
gucauccguccuucaaguuugcgcuuccgcaagcguguacgccucgggcu
uugaaguauguuuuagcucucagagcuucuacacauuucgauaucagaau
uucugauauuagcccuuuuaauaaagcaguuacuguaccuaagaacagua
agacagaucguuguauugcuaucgaaccugguuggaauauguuuuuccaa
cuggguaucgguggcauucuacgcgaucgguugcguugcugggguaucga
ucugaaugaucagacgauaaaucagcgccgcgcucacgaaggcuccguua
cuaauaacuuagcaacgguugaucucucagcggcaagcgauucuauaucu
cuugcccucugugagcucuuauugcccccaggcugguuugagguucuuau
ggaccucagaucaccuaaggggcgauugccugacgguaguguuguuaccu
acgagaagauuucuucuauggguaacgguuacacauucgagcucgagucg
cuuauuuuugcuucucucgcucguuccguuugugagauacuggacuuaga
cucgucugaggucacuguuuacggagacgauauuauuuuaccguccugug
cagucccugcccuccgggaaguuuuuaaguauguugguuuuacgaccaau
acuaaaaagacuuuuuccgaggggccguucagagagucgugcggcaagca
cuacuauucuggcguagauguuacucccuuuuacauacgucaccguauag
ugaguccugccgauuuaauacugguuuugaauaaccuauaucggugggcc
acaauugacggcguaugggauccuagggcccauucuguguaccucaagua
ucguaaguugcugccuaaacagcugcaacguaauacuauaccugaugguu
acggugauggugcccucgucggaucgguccuaaucaauccuuucgcgaaa
aaccgcggguggauccgguacguaccggugauuacggaccauacaaggga
ccgagagcgcgcugaguuggggucguaucucuacgaccucuucucgcguu
gucucucggaaaguaacgauggguugccucuuagggguccaucggguugc
gauucugcggaucuauuugccaucgaucagcuuaucuguaggaguaaucc
uacgaagauaagcaggucuaccggcaaauucgauauacaguauaucgcgu
gcaguagccguguucuggcacccuacggggucuuccagggcacgaagguu
gcgucucuacacgaggcguaaccugggagggcgccaauauggcgccuaau
ugugaauaaauuaucacaauuacucuuacgagugagagggggaucugcuu
ugcccucucuccuccca

<<<<<<<<<<<..>>>>>>>>.>>>....<<<<<<<<.....<<<<<<<<
<<<<<<<<<<.<<<<.....<<<<<<<.<<..<<<<<.<<<<<..<..<<
<<<<<.............>>>>.<<<.<<<.......>>>.>>>.>>>..
>.....>>>>>.>>>>>>>>>>>>>>...<<<<<<.<<...<.<<<.<..
<<<<.<<<.<<..<<<<<<<<<<.....>>>>>>>>>>..>>>>>..>>>
>....>.>>>..>..<.<<<.....<<..<<<......>>>..>>....>
>>.>...>>.>>>>>>...<<<<<.<<<<<<...<<<<<.....>>>>>.
..>>>>>>...>>>>>...>>>>>>>..<<..<<<<<<<<...<<<<...
.>>>>.....>>>.>>>>>..>>..<<.<<<<<<<<<<<<....>>>>>>
>>>>>>>>>>>>>.>>>>>>>>>>.<<<<<.<<<..<.<<.<<<<<....
>>>>>.>>.>..>>>.>>>>><<<<<<<<..........>>>>>>>>...
..<<<<<.<<<..<<<<<.......<<<<<<<....>>>>>>>.....>>
>>>..>>>.>>>>><<<<.<<<.....<<<<<...>>>>>...>>>>>>>
...>>>>>>>><<<<<<<<.<<<<<<<<<<<.<<<<<<<<....<<<<..
<<<..<<<<<<<<<...>>>>>>>>>..>>>..>>>>.....>>>>>>>>
.>>>>>>>>.>>>.<<<<<<<<<<...<<...<.<<<<<.<<<..<<<<<
<<<<<....>>>>>>..>>>>.>>>>>>>>.>...>>...>>>>>>.>>>
>.>>>>>>>>....<....<<<<..<<<..<<<<<<<<<<<<.<<<....
.>>>.>>>>>>>>>>>>...>>>..>>>><<<<..<<<<.......>>>>
..>>>>..<<..<<<<...<<<<<<<.<<<<<.<<<<<<<<<...<.<<<
<<....>>>>>.>..>>>>>>.>>>.>>>>>.....>>>>>>>.>>>>..
......<<<<......<<<.<<<.<<..<<<<.<<<<<<....<<<<<<<
<<....<<<<<<<<<<<.<<<.<<<<..<..<<<<<<......>>>>>>.
.>..>>>>>>>..>>>>.>>>..>>>>..>>>>.>>>>>..>>>>>>>>>
>..>>.>>>.>>>.......>>>>...>>......>..............
...<<<.<.....<<..<<<......>>>..>>...>.>>>.........
.....<<<<<<.....>>>>>>......<<<<<<<<<<<<.......>>.
>>>>..<<<.<<<<<<<...>>>>>>><<<<<.....<<<<.....<<.<
<<<<..<<<<<.<<<.<<<<<<....>>>>>>...>>>..>>>.<<<<<<
<....>>>>>>><<.<<<<<.<<<..<<.<<<<<...<..<<<<...>>>
>....>...>>>>>..>>...>>>.>>>>>.>>>>..>>>>>>>....>>
>>...>>>>><<<.<<<.....>>>.>>>.>>>...>>>>>>...<<<.<
<<<...<<.<<<<<<<<.<<<<<<......>>.>>>>>>>>>>>.>.>>.
.>>>>.>>><<<<...<<<<<<<.<<<<<<.....>>>>>>..<<<<...
..<<.<<<<<<<<<<...>>>>>>>>>>.>>....>>>>.>>.>>>>>..
>>>>......<<<<<<<<.<<<<<<<....>>>>.<<<<<<.....>>>>
>>........>>>.>>>>>>>><<<<<<<<<<<....>>>>>>>>>>>.<
<<<<<.<<<<.<.<<<<<<<<<<..((((>>>>>>>.>>>.>.>>>>..<
<<<<..<<....<<<.<<<...<<<.<<<<<.<.<<<.<.<<<<.<<<<<
<<<..<<<....>>>.>>>>>>>>>>>>.>.>>>.>.>>>>>.>>>..>>
>>>>..>>..>>>>>...<<<.<<<<<<<.<<<<..<<<.........<<
<..<<<<...<<<<.<<<<.<<<<<<<.<<...>>.>>>>>>>.>>>>.>
>>>..>>>>>>>.......>>>...>>>>..>>>>>>>...<<<<<<..<
<<<<<<<.......>>>>>>>>....>>>>>>.....>>>..>>>>>>..
<<<<<<<<<<...>>>>>>>>>>.<<<....<<<<<<...<<.......>
>..>>>>>>..>>>..<<<<<<<<<...<<<<<.<<.<<<.....>>>.>
>..>>>>>.>>>>.>>>>>....<<<..<<<<<...>>>>>..>>>.<<<
<.<<<<...>>>>>>>>.<<<<<<.....<<<...<<<<<....>>>>>.
>>>.>>>>>>..........<<<<<..<<<<<<.<<<.<<<<...<<<<.
<<<<<<<......>>>>>>>..>>>>...<<<<.<<<.....<<<..<<<
<<<<<<.....>>>>>>>>>..>>><<<<<<<.<<.<.<<<....<<<<<
<<<<<...>>>>>>>>>>>>>.>.>>.>>>>>>>..>>>.>>>><<<<<<
<<.<<<<....>>>>....<<<<<<<<.<<<<.....>>>>>>>>>>>>>
>>>>>>>.>>>>...<<<<.<<<..<<<<<<<..<.<<.<<.<<<<<<<<
<<<<.......>>>>>>>>>.<<<<<<<<<<<....>>>>>>>>>>>.((
((..>>>.>>.>>>....>>>>>>>...>>>.>>>>.>>>.>><<<<<..
.<<<<<<<...)))).>>>>>>>...>>>>><<<.<<.<<<<.)))).>>
>>.>>.>>>>>>>...<<..<<<<<......>>>>>..>>>>>>>.<<<<
.<<<<<<.<<<...<<<<<...>>>>>...>>>.>>>>>>.<<<<<<<..
.>>>>>>>..>>>>...............<<<<<<<<<.<<<<..<<<<.
..<<.<<<<<.<<<<.<<<<<<<<<<<<<<<<<<<<<.......>>>>>>
>>>>>>.>>>>>>>>>...>>>>>>>>>.>>.<<<.<<<<<<..<<<<<.
<<<<<....>>>>>>>>>>..>>>>>>.>>>.<<<<<..<<<<.<<<<<.
<<<<....>>>>.>>>>>..<<.<<..<<<.<<<<<<.<<<.....>>>.
>>>>>>..>>>..>>.>>..<<<<<<<<.<<<.<<<<<<<<<<.<<....
>>.>>>>>>>>>>>>>..>>>>>>>>.>>>>.<<<...<<<.<<<<<<<<
..<...........>....>>>>>>>>....>>>...<<<<...<<<..<
<........>>..>>>...>>>>...>>>..>>>>>..>>>>..>>>><<
<<..<<<<.<<..<<<<..<<<<..<<<<.<<......>>.>>>>.>>>>
>>>>.>.><<<<<.<<<<<<<<<<<...<...<<<<<<......>>>>>>
..>...>>>>>>>..>>>>.>>>>><<<.<<<<<..<.<<.........>
>.>...>>>>>>>>>>>>..<<...<<<<......<<<<<<..<<.<<.<
<<.<<<<.<<<<<<.<<.....<<<<......>>>>>>.>>>>>>>>>>>
>>.>>>>..>>>>>>...<<<<<.<<<<<<<<<.<<<<<.<<<<<<.<<<
<.<<..<<<<<.<<.......>>.>>>>>.....>>.>>>>.>>>.>>>>
>>>>..>>>>.>>>>>....>>>>><<<<<<<<<<..<<<.<<<<.....
.....>>>>.>>>.<<<<<....>>>>>.>>>>>.>>>>>.....>>>>.
<<<<<<<.<<<.<<<<..<<<<<<<<<....>>>>>>>>>..>>>>>>>.
..>>>>>>>.....>><<<<<<....<<<.....>>>.>>>>>>>>>><<
<<<.<<<...<<<.<<<<<<<...<<<<.<<<<<<<.<<.<<......>>
.>>...>>>>>>>.>>>>....>>>>>>>..>>>...>>>...>>>>>>>
>>>>>>>.<<<<<<<<<<.<<<<....>>>>...>>>>>>>>>>..<<<<
<<<<<<<.....>>>>>>>>>>><<<<<..<<<<<<...>>>>>>..<<<
<<<<<........>>>>>>>><<<<....>>>><<<<<<<<.........
...>>>>>>>>.>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7lhd Structural Assembly of Q beta Virion and Its Diverse Forms of Virus-like Particles.
• Resolution: 4.6 Å
• Binding residue (original residue number in PDB): K60 Y62 Q98
• Binding residue (residue number reindexed from 1): K60 Y62 Q98

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0005198 structural molecule activity
• GO:0030371 translation repressor activity

Biological Process

• GO:0006417 regulation of translation
• GO:0017148 negative regulation of translation

Cellular Component

• GO:0019028 viral capsid
• GO:0039617 T=3 icosahedral viral capsid

External links

• PDB: RCSB:7lhd, PDBe:7lhd, PDBj:7lhd
• PDBsum: 7lhd
• PubMed: 35215818
• UniProt: P03615|CAPSD_BPQBE Capsid protein