Structure of PDB 6yxy Chain EA Binding Site BS01

Receptor Information
>6yxy Chain EA (length=532) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFNLPRERQILGGLHADWRTQMKRSGSILNDITPALPDTKRTEEQRRRVA
GWRPVVKLLGDQRLRIAIVGRMNSGKSSLFNLLRLEPTVPGRSNVVRDFD
GITRDSVEGQAQLEGMHFTIIDTPGMVQGRMVEEAFRTVETADAAIFVTA
VDEDIMPEELSLMQYLHLKHMPVVLLANKMDLIQEEEEEAVLDRYNSLGF
GNAIPFSARRKSGLEMLAAVLEPLYHIHAMHKVENDWDIEDLAMQGDESA
MEEIRERNCSDRFIRIAIVGRTNSGKSSLVNRLVGFERNRAVDEKNSTRD
PVELPCSYKGRKLKLIDTAGLARHRYRADRDFIGRIHGLSVNEIRFAHVV
IVVFDATEGHPNKYDMAVLHSVAAEGRPFLLCANKWDAVLDQSATAEAID
FKIKRQVREVKYSNAVVVSAHTGLNLTLLMDQALELYDKWNKRVRRAELT
RLWRKMEKSVIIPYHVARIGRITQVNTRPPTFLLQLQTKNDSNTLPKALQ
EMMKNTLVEEFDFRGVPIRLIQEVKDSNPDYI
Ligand information
>6yxy Chain AA (length=903) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6yxy Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
R68 S69 G70 S71 P134 R367 H368 R369 Y370 R389 N406 K407 A411 H414 R452 R490 R498 R512 R515 V519 K541 Y575 I576
Binding residue
(residue number reindexed from 1)
R24 S25 G26 S27 P90 R323 H324 R325 Y326 R345 N362 K363 A367 H370 R408 R446 R454 R468 R471 V475 K497 Y531 I532
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6yxy, PDBe:6yxy, PDBj:6yxy
PDBsum6yxy
PubMed32679035
UniProtQ57TZ4

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