Structure of PDB 8wus Chain E Binding Site BS01

Receptor Information
>8wus Chain E (length=453) Species: 11801 (Moloney murine leukemia virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLG
IKPHIQRLLDQGILVPCQSPWNTPLLPVKKPGTNDYRPVQDLREVNKRVE
DIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWR
DPEMGISGQLTWTRLPQGFKNSPTLFNEALHRDLADFRIQHPDLILLQYV
DDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLL
KEGQRWLTEARKETVMGQPTPKTPRQLREFLGKAGFCRLFIPGFAEMAAP
LYPLTKPGTLFNWGPDQQKAYQEIKQALLTAPALGLPDLTKPFELFVDEK
QGYAKGVLTQKLGPWRRPVAYLSKKLDPVAAGWPPCLRMVAAIAVLTKDA
GKLTMGQPLVILAPHAVEALVKQPPARMTHYQALLLDTDRVQFGPVVALN
PAT
Ligand information
>8wus Chain B (length=115) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggccguagugcuugcucugaguuuuagagcuagaaauagcaaguuaaaau
aaggcuaguccguuaucaacuugaaaaaguggcaccgagucggugcucac
agcgugcucagucug
....................<<<<<<..<<<<....>>>>....>>>>>>
..<<.....>>.......<<<<....>>>>.<<<<<<...>>>>>>....
...............
Receptor-Ligand Complex Structure
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PDB8wus Structural basis for pegRNA-guided reverse transcription by a prime editor.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
Y64 L99 V101 V112 D114 R116 V129 N131 Y133 G191 F192 K193 P196 R311 Y325 K329 K397 K425
Binding residue
(residue number reindexed from 1)
Y41 L76 V78 V89 D91 R93 V106 N108 Y110 G168 F169 K170 P173 R288 Y302 K306 K374 K402
Enzymatic activity
Enzyme Commision number ?
External links