Structure of PDB 8uu4 Chain E Binding Site BS01

Receptor Information
>8uu4 Chain E (length=204) Species: 1642 (Listeria innocua) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLSLLKQDGTNAGEITLNDTVFGIEPNEKVVVDVILSQRASLRQGTHKVK
NRSEVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYAYKLP
KKVRRLAIKSILSSKVNEEKLVVLEGLTFDAPKTKEFAAFLKNISVDTKA
LIVVAGESENVELSARNLQGITVIPAESISVLEVAKHDKLIITKAAVEKV
EEVL
Ligand information
>8uu4 Chain A (length=2903) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaaga
aggacgggacuaacaccgauaugcuuuggggagcuguacguaagcguuga
uccagagauuuccgaaugggggaacccacuaucuuuagucggauaguauc
cuuacgugaauacauagcgugaggaaggcagacccagggaacugaaacau
cuaaguaccuggaggaagagaaagaaaaaucgauuuccugaguagcggcg
agcgaaacggaaagagcccaaaccaagaagcuugcuucuugggguuguag
gacacucuauacggaguuacaaaagaaaguuauaaaugaagcggucugga
aaggcccgccaaagacgguaacagcccgguaguugaaauggcuuucccuc
cagaguggauccugaguacgacggaacacgugaaauuccgucggaauccg
ggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaacc
aguaccgugagggaaaggugaaaagcaccccggaaggggagugaaacagu
uccugaaaccgugugccuacaaguaguuagagcccguuaaugggugauag
cgugccuuuuguagaaugaaccggcgaguuacgauuuguugcaagguuaa
gcggaaaaagcggagccguagcgaaagcgagucugaauagggcgcauaag
uaacaggucguagacccgaaaccaggugaucuacccauguccaggaugaa
gguaagguaauacuuacuggagguccgaacccacgcacguugaaaagugc
ggggaugagguguggguagcggagaaauuccaaucgaacuuggagauagc
ugguucucuccgaaauagcuuuagggcuagccucgagguaaagagucaug
gagguagagcacuguuuggacuaggggcccgguuaccgaauucagauaaa
cuccgaaugccauguacuuauacucgggagucagacugcgagugauaaga
uccguagucgaaagggaaacagcccagaccaccaguuaagguccccaaau
auauguuaaguggaaaaggaugugggguugcuuagacaaccaggauguug
gcuuagaagcagccaccauugaaagagugcguaauagcucacuggucgag
ugaccccgcgccgaaaauguaccggggcuaaacauauuaccgaaacugug
gaugaaccgguucgugguaggagagcguucuaagggcggugaagucagac
cggaaggacugguggagcgcuuagaagugagaaugccgguaugaguagcg
aaagaagggugagaaucccuuccaccgaauaucuaagguuuccugaggaa
ggcucguccgcucaggguuagucgggaccuaagccgaggccgauaggcgu
aggcgauggacaacagguagagauuccuguaccagugcuaauuguuuaac
cgauggggugacacagaaggauagggaaucgcacgaauggaaaugugcgu
ccaagcagugagugugagaaguaggcaaauccgcuucuugcgaagcauga
gcugugauggggaagcggaaguuccugauuucacgcugucaagaaaagcc
ucuaggaagaguaguacugcccguaccgcaaaccgacacagguagaugag
gagagaauccuaaggugagcgagagaacucucguuaaggaacucggcaaa
augaccccguaacuucgggagaaggggugcucuauuagggugcaagcccg
agagagccgcagugaauaggcccaggcgacuguuuagcaaaaacacaggu
cucugcaaaaccguaaggugacguauaggggcugacgccugcccggugcu
ggaagguuaagaggagugcuuagcuucggcgaagguacgaauugaagccc
caguaaacggcggccguaacuauaacgguccuaagguagcgaaauuccuu
gucggguaaguuccgacccgcacgaaaggcgcaacgaucugggcacuguc
ucaacgagagacucggugaaauuauaguaccugugaagaugcagguuacc
cgcgacaggacggaaagaccccguggagcuuuacugcaaccugauaugga
auguuuguaccgcuuguacaggauagguaggagccgaagagacgugugcg
cuagcauacgaggaggcaauggugggauacuacccuggcuguaugaccau
ucuaacccgccacgcuaagcgcguggggagacagugucaggugggcaguu
ugacuggggcggucgccuccuaaagaguaacggaggcgcccaaagguucc
cucagaauggauggaaaucauucgcagaguguaaaggcacaagggagcuu
gacugcgagacugacaagucgagcagggacgaaagucgggcuuagugauc
cggugguuccgcauggaagggccaucgcucaacggauaaaagcuaccccg
gggauaacaggcuuaucucccccaagaguccacaucgacggggagguuug
gcaccucgaugucggcucgucgcauccuggggcuguagucggucccaagg
guugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacguc
gugagacaguucggucccuauccgucgcgggcgcaggaaauuugagagga
gcuguccuuaguacgagaggaccgggauggacacaccgcugguguaccag
uuguuccgccaggagcaucgcuggguagcuauguguggcagggauaaacg
cugaaagcaucuaagcgugaagccccccucaagaugagauuucccauuuc
uucggaaaguaagaucccugaaagaugaucagguagauagguuuggagug
gaaguguagcgauacauggagcggacaaauacuaaucgaucgaggacuua
acc
<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<.....
.<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<
<<<<<<<.........>>>>>>>>>.>>....<<<<<<.....<<....>
>......>>>>>.>.........<<....>>..<<<<<......<<....
.>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<<
<<<<<<<<....<<<<........<<<<<<<<<.<<<.....<<<<....
..>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>.>>>
>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......<
<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]...........
....<<....>>....]].........<<<<....>>>>...........
..}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>>
>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...
<<.......>>...>>>...<<....>>..<<<<.....>>>>......>
>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....
<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>>
>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>
.>>..<<<<<<....<<<<<....>>>>><<<<<<<<.....<<<<<<<<
<.....<<<...<<<<<<<<...<<.<<<.>>>..>>...>>>>>>>>..
>>.>.....>>>>>.>>>>...>>>>>>.>>..<<<<<<<.<<......>
>.>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.....
<<<<<<...........<<..<<<<<<<<<<.......<<<<<.<<...<
<<<.......>>>>...>>.........<<......>>...>>>>>...>
>>>>>>>>>.>>...........))).....>>>>>>.>>>...>>>>>>
><<<<<<..>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<
<....>>.>>>>>...>>.>>>>>>>..>.....>>>>>><......<<.
...<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...
<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>..
.>>>...>>...<<<<<........>>>>>))<<<<<<<<.<<......<
<...<<<<<...<<<<..<<<..<<<<<.<<<<<...(((....>>>>>.
<<..<<<<<..<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>..
>>>>>...>>...........>>>>>...>>>...>>>>........>>>
>>..>>..>>.>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<
<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<.........<..
...<<<<<.....<..>......>>>>><<<<<....<<<<....>>>>.
..>>>>>............<<<<<<<<<..<<<.........>>>..<<<
<<<<.....<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<
<<..<<<<..<<...<<<<<<.<<<..>>>..>>>>>>...>>..>>>>>
>>>>..>>>>><<<<<<.......>>>>>>........<...........
<<<<<<.....>>>>>>.....>....>>>>...>>.>>>>>>>..>..>
>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<
<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<
<<<..<<<<<.<<<...........<<<<<..<<<.......<<<<<<<.
...>>>>>>>....>>>............>>>>>..>>>.>>>>>..>>>
>>....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>.
.<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<
<...<<<<<.<......>>>>>>.....<<.[.(((>>....>>>>>>>.
..<<<<..<<<<....>>>>..>>>>.<<<....>>>.>>)))]......
<<<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>
>>.......<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>
>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>
>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<
....>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<.
.<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<
<<<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<
<<...........>>>>>...>>>>.>>>>.......>>>>>>>..<<<<
<..>>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<<.
...<<<<<....>>>>>...>>...>>>>>.>>>...>>>>....>>>>>
>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uu4 Mechanistic insights into the alternative ribosome recycling by HflXr.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R41 R45 Q46 T48 V51 R54 S55 V57 R58 G59 K63 Q67 K68 G71 R72 A73 R74 G76 Q82 R84 V88 V89 F90 P92 R95 Y99 K104 V105 R106 K135 T136 K137 K151 L165 R168 N169 L170 Q171 E179 S180
Binding residue
(residue number reindexed from 1)		R39 R43 Q44 T46 V49 R52 S53 V55 R56 G57 K61 Q65 K66 G69 R70 A71 R72 G74 Q80 R82 V86 V87 F88 P90 R93 Y97 K102 V103 R104 K133 T134 K135 K149 L163 R166 N167 L168 Q169 E177 S178
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8uu4, PDBe:8uu4, PDBj:8uu4
PDBsum8uu4
PubMed38407413
UniProtA0A0U4VSH7

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