Structure of PDB 8u8u Chain E Binding Site BS01

Receptor Information
>8u8u Chain E (length=985) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAV
MLGWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQDQDAGTIE
RCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPP
VNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSV
EKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSL
YPFLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQ
RVSGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEALGAPEALREQPW
PLPVQMELGKLLAEMLVQATQMPCSSRLVPVLYHVYSFRNVQQIGILKPH
PAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTKLMRTV
EGATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQLFQAK
GCPQLGVPAPPSEAPQPPEAHLPHSAAPARKAELRRELAHCQKVAREMHS
LRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARAL
LEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDS
ADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPVHQDGS
CNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQDAQRG
MRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEF
VWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPL
GVPVIQPYRLDSRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLT
FVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEP
QKILEASQLKETLQAVPKPGAFDLEQVKRSTYFFS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8u8u Structural basis for substrate binding and selection by human mitochondrial RNA polymerase.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		N614 G817 H1150
Binding residue
(residue number reindexed from 1)		N390 G593 H905
External links
PDB RCSB:8u8u, PDBe:8u8u, PDBj:8u8u
PDBsum8u8u
PubMed39164235
UniProtO00411|RPOM_HUMAN DNA-directed RNA polymerase, mitochondrial (Gene Name=POLRMT)

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