Structure of PDB 8snh Chain E Binding Site BS01

Receptor Information

>8snh Chain E (length=468) Species: 287 (Pseudomonas aeruginosa)

PAYNYKVVRQFAIMTVVWGVIGMGLGVLIASQLVWPQMNFDLPWTSFGRL
RPLHTNLVIFAFGGCALFATSYYTVQRTCQVRLFSDTLAAFTFWGWQAVA
VILLVSLPLGNTTTKEYAEIEFTGAIWLAIVWVAYAVVFFGTLIKRKVKH
IYVGNWFFGSFILTTAMLHIVNHMSLPVSWFKSYSMYSGATDAMVQWWYG
HNAVGFFLTTGFLGMMYYFVPKQAGRPVYSYRLSIVHFWALITLYIWAGP
HHLHYTALPDWAQSLGMVMSLILLAPSWGGMINGMMTLSGAWHKLRDDPI
LRFLVVSLAFYGMSTFEGPMMAIKTVNALSHYTDWTIGHVHAGALGWVAM
ITIGSLYHLIPKVYGVEKMHSVGLINAHFWLATIGTVLYIASLWVNGITQ
GLMWRAVNEDGTLTYSFVESLVASHPGFIVRLVGGGFFLTGMLLMSYNTW
RTVRQARPEGILAAARMA

Ligand information

• Ligand ID: CU
• InChI: InChI=1S/Cu/q+2
• InChIKey: JPVYNHNXODAKFH-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Cu+2]
  CACTVS 3.341: [Cu++]
• Formula: Cu
• Name: COPPER (II) ION
• DrugBank: DB14552
• PDB chain: 8snh Chain E Residue 501

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8snh Structure of the bc 1 - cbb 3 respiratory supercomplex from Pseudomonas aeruginosa.
• Resolution: 2.7 Å
• Binding residue (original residue number in PDB): H208 H258 H259
• Binding residue (residue number reindexed from 1): H201 H251 H252
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 7.1.1.9: cytochrome-c oxidase.

Gene Ontology

Molecular Function

• GO:0004129 cytochrome-c oxidase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006119 oxidative phosphorylation
• GO:0009060 aerobic respiration
• GO:0015990 electron transport coupled proton transport
• GO:0022904 respiratory electron transport chain

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane

External links

• PDB: RCSB:8snh, PDBe:8snh, PDBj:8snh
• PDBsum: 8snh
• PubMed: 37751552
• UniProt: Q9HWP8