Structure of PDB 8s9v Chain E Binding Site BS01

Receptor Information
>8s9v Chain E (length=678) Species: 1148 (Synechocystis sp. PCC 6803) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNFHNPYNFVPALPRDGITGDLGDCAPAGHSYYHGDKYSGRIAVKLTTVT
PLLIPDASKEEINNNHKTYPVRIGKDGKPYLPPTSIKGMLRSAYEAVTNS
RLAVFEDHDSRLAYRMPATMGLQMVPARIEGDNIVLYPGTSRIGNNGRPA
NNDPMYAAWLPYYQNRIAYQMAEHGDHVRFWAERYTRGNFCYWRVRQIAR
HNQNLGNRPERGRNYGQHHSTGVIEQFEGFVYKTNKNIGNKHDERVFIID
RESIEIPLSRDLRRKWRELITSYQEIHKKEVDRGDTGPSAVNGAVWSRQI
IADESERNLSDGTLCYAHVKKEDGQYKILNLYPVMITRGLYEIAPVDLLD
ETLKPATDKKQLSPADRVFGWVNQRGNGCYKGQLRIHSVTCQHDDAIDDF
GNQNFSVPLAILGQPKPEQARFYCADDRKGIPLEDGYDRDDGYSDSEQGL
RGRKVYPHHKGLPNGYWSNPTEDRSQQAIQGHYQEYRRPKKDGLEQRDDQ
NRSVKGWVKPLTEFTFEIDVTNLSEVELGALLWLLTLPDLHFHRLGGGKP
LGFGSVRLDIDPDKTDLRNGAGWRDYYGSLLETSQPDFTTLISQWINAFQ
TAVKEEYGSSSFDQVTFIKASGQSLQGFHDNASIHYPRSTPEPKPDGEAF
KWFVANEKGRRLALPALEKSQSFPIKPS
Ligand information
>8s9v Chain F (length=37) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acugaaacuguaguagaaccaaucggggucgucaaua
.....................................
Receptor-Ligand Complex Structure
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PDB8s9v RNA targeting and cleavage by the type III-Dv CRISPR effector complex.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
P166 A168 S196 K198 G199 R202 R226 W270 F307 T351 N354 I355 N357 K358 H359 R362 Y390 H394 S414 V451 M452 I453 R455 G487 W488 V489 C496 Y497 I528 L529 G530 Q531 P532 K533 Q536 Y540 K571 Y573 R619 G663 G664 G665 K666 P667 Y753 F767 F770
Binding residue
(residue number reindexed from 1)
P55 A57 S85 K87 G88 R91 R115 W159 F190 T234 N237 I238 N240 K241 H242 R245 Y273 H277 S297 V334 M335 I336 R338 G370 W371 V372 C379 Y380 I411 L412 G413 Q414 P415 K416 Q419 Y423 K454 Y456 R502 G546 G547 G548 K549 P550 Y636 F650 F653
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:8s9v, PDBe:8s9v, PDBj:8s9v
PDBsum8s9v
PubMed38637512
UniProtQ6ZED5

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