Structure of PDB 8r6s Chain E Binding Site BS01

Receptor Information
>8r6s Chain E (length=1091) Species: 3728 (Sinapis alba) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANLVFHNKVIDGTAIKRLISRLIDHFGMAYTSHILDQVKTLGFQQATATS
ISLGIDDLLTIPSKGWLVQDAEQQSLILEKHHHYGNVHAVEKLRQSIEIW
YATSEYLRQEMNPNFRMTDPFNPVHMMSFSGARGNASQVHQLVGMRGLMS
DPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTR
RLVEVVQHIVVRRTDCGTIRGISVSPRNKSRMMSERIFIQTLIGRVLADD
IYIGSRCVAFRNQDLGIGLVNRFITFGTQSISIRTPFTCRSTSWICRLCY
GRSPTHGDLVELGEAVGIIAGQSIGEPGAEHVRAPYNGKIKFNEDLVHPT
RTRHGHPAFLCYIDLSVIIESEDIIHSVTIPPKSFLLVQNDQYVESEQVI
AEIRERVRKYIYSDSEGEMHWSTDVSHAPEFTYSNVHLLPKTSHLWILSG
GSCGSSLILFSIHKDQDQMNIPFSDLLAKRRRNRFLIPISVEIPINGIFR
RNSIFAFFDDPRYRRKSSGILKYDRFFFIPEEVHILPESSAIMVENYSII
GVDTRITLNIRSQVGGLIRVERKKKRIELKIFSGDIHFPDKTDKISRHSG
ILIPPGKNWIYVQRITPTKKKFFVLVRPVATYEIADSINLATLFPKDLFR
EKDNIQLRVFNYILYGNGKPTRGISDTSIQLVRTCLVLNWVRAFFVEVNT
KGLIRDFIRIGLRKRNNPMNPFYHGTIRMFSLLILSSSNCFRIGTIKNSS
GPLGTAIQISNFYSFLPLLTYNQISVIKYLQLDNFKYIFQVIHSYLIDEN
GRIFNLDPYSNLVLNPFKLNWYFLHQNYNTIISLGQFFCENVCIAKKEPY
LKSGQVLIVQRDSVVIRSAKPYLATPGAKVHGHYREILYEGDTLVTFIYE
GLPKVEQVLEVSLNLEKRIKGWNRCITRILGIPWGFLIGAELTIVQSRIS
LVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEEGMSNVFLPGELIG
LLRAERTGRALEEAICYRAVLLGITRASLNTQSFISEASFQETARVLAKA
ALRGRIDWLKGLKENVVLGGVIPAGTGFNKGDILFYHREFC
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8r6s Chain E Residue 8001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8r6s Structure of the plant plastid-encoded RNA polymerase.
Resolution2.49 Å
Binding residue
(original residue number in PDB)		C220 C293 C300 C303
Binding residue
(residue number reindexed from 1)		C216 C289 C296 C299
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0009507 chloroplast

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8r6s, PDBe:8r6s, PDBj:8r6s
PDBsum8r6s
PubMed38428394
UniProtA0A6C0M829

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