Structure of PDB 8qdv Chain E Binding Site BS01

Receptor Information
>8qdv Chain E (length=225) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKN
VVGARRSSWRVVSSIEQKTKQQMAREYREKIETELRDICNDVLSLLEKFL
IPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEI
SKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDT
LSEESYKDSTLIMQLLRDNLTLWTS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8qdv 14-3-3zeta binding increases cytosolic phospho-Tau solubility by decreasing its condensation, aggregation, and microtubule association
Resolution2.5 Å
Binding residue
(original residue number in PDB)		R56 R127 Y128 L172 N173 N224
Binding residue
(residue number reindexed from 1)		R56 R122 Y123 L167 N168 N219
External links
PDB RCSB:8qdv, PDBe:8qdv, PDBj:8qdv
PDBsum8qdv
PubMed
UniProtP63104|1433Z_HUMAN 14-3-3 protein zeta/delta (Gene Name=YWHAZ)

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