Structure of PDB 8pje Chain E Binding Site BS01
Receptor Information
>8pje Chain E (length=194) Species:
9606
(Homo sapiens) [
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MGSMGDTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGE
YRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVE
PKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTG
LIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
Ligand information
>8pje Chain F (length=13) Species:
11320
(Influenza A virus) [
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PKYVKQNTLKLAT
Receptor-Ligand Complex Structure
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PDB
8pje
A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation.
Resolution
1.7 Å
Binding residue
(original residue number in PDB)
F13 D57 W61 R71 Y78 H81 N82 V85
Binding residue
(residue number reindexed from 1)
F17 D61 W65 R75 Y82 H85 N86 V89
External links
PDB
RCSB:8pje
,
PDBe:8pje
,
PDBj:8pje
PDBsum
8pje
PubMed
38819988
UniProt
P01911
|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)
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