Structure of PDB 8ott Chain E Binding Site BS01

Receptor Information
>8ott Chain E (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSA
VMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>8ott Chain I (length=144) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggagaatcccggtctgcaggccgctcaattggtcgtagacagctctagca
ccgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaagggg
attactccctagtctccaggcacgggtcacgtgcatacatcctg
Receptor-Ligand Complex Structure
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PDB8ott Cooperation between bHLH transcription factors and histones for DNA access.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		R40 Y41 G44 V46 R49 R52 K56 R63 K64 L65 P66 R69
Binding residue
(residue number reindexed from 1)		R2 Y3 G6 V8 R11 R14 K18 R25 K26 L27 P28 R31
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8ott, PDBe:8ott, PDBj:8ott
PDBsum8ott
PubMed37407816
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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