Structure of PDB 8oh5 Chain E Binding Site BS01

Receptor Information
>8oh5 Chain E (length=584) Species: 1123288 (Sporomusa ovata DSM 2662) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKVRVGLGSCGIAAGGRKVMDRLAQEIKNHGKEIELLPTGCIGMCFYEPI
VDVFDGDKVYSYANVTADMATEIFNSHIIGGQPLTQYIVSTTEKPYTILA
KQVRIALRNCGVIDPENVDEYKANDGYKALSKALKEMTPEEVIEEIKVAG
LRGRGGAGFPTWFKWNAARQSKGEIKYVVCNADEGDPGAFMDRSVLEGDP
HALLEGMAICGYAIGANEGHIYCRAEYPLAIKRLEIAIADAKQRNLLGKN
IMGTNFSFDMKIKKGAGAFVCGEETALIASLEGERGMPRLKPPFPAQSGF
WGKPTNINNVETFANVPWIMYNGGSAYAAYGTEKSKGTKVFALAGKIKNG
GLVEVPMGMSLREVIYDIGGGILNDREFKAVQMGGPSGGCIPKQLLDTPV
DYDSINKTGAIMGSGGMIVMDETTCMVDMARFFLDFTVKESCGKCIYCRI
GTKRMLEILERITTGEGREGDIEELEELSISIKDGSLCGLGQTAPNPVLT
TIRYFRDEYEAHIRDKKCPAKSCKPLLTYTINQDNCKGCTLCAQKCPVQA
ITGEKKKPHVIDQALCTKCGNCASVCRLDAVCIE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8oh5 Chain E Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8oh5 Molecular architecture and electron transfer pathway of the Stn family transhydrogenase.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		C425 H512 C518 C523
Binding residue
(residue number reindexed from 1)		C425 H512 C518 C523
Annotation score1
Enzymatic activity
Enzyme Commision number 1.12.1.2: hydrogen dehydrogenase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0047985 hydrogen dehydrogenase activity
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:8oh5, PDBe:8oh5, PDBj:8oh5
PDBsum8oh5
PubMed37673911
UniProtA0A0U1KYM9

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