Structure of PDB 8jnr Chain E Binding Site BS01

Receptor Information
>8jnr Chain E (length=195) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVIDREGVYEISLSPTGVSRVCLYPGFVDVKEADWILEQLSQDVPWKQRT
DITYQQPRLTAWYGELPYTYSRITMEPNPHWHPVLRTLKNRIEENTGHTF
NSLLCNLYRNEKDSVCWHSDDEPSLGRSPIIASLSFGATRTFEMRKKPER
VKIPLDHGTLLIMEGATQADWQHRVPKEYHSREPRVNLTFRTVYP
Ligand information
Receptor-Ligand Complex Structure
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PDB8jnr The Molecular Basis of Human ALKBH3 Mediated RNA N1-methyladenosine (m1A) Demethylation
Resolution3.66 Å
Binding residue
(original residue number in PDB)		R131 Y143 C189 H191
Binding residue
(residue number reindexed from 1)		R58 Y70 C116 H118
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
1.14.11.54: mRNA N(1)-methyladenine demethylase.
Gene Ontology
Molecular Function
GO:0051213 dioxygenase activity
Biological Process
GO:0006281 DNA repair
GO:0006307 DNA alkylation repair

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Molecular Function
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Biological Process
External links
PDB RCSB:8jnr, PDBe:8jnr, PDBj:8jnr
PDBsum8jnr
PubMed38158383
UniProtQ96Q83|ALKB3_HUMAN Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Gene Name=ALKBH3)

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