Structure of PDB 8jlb Chain E Binding Site BS01

Receptor Information
>8jlb Chain E (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSA
VMALQEASEAYLVGLFEDTNLAAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>8jlb Chain I (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatcgat
Receptor-Ligand Complex Structure
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PDB8jlb Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Resolution2.36 Å
Binding residue
(original residue number in PDB)
Y41 G44 V46 L65 R69
Binding residue
(residue number reindexed from 1)
Y3 G6 V8 L27 R31
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8jlb, PDBe:8jlb, PDBj:8jlb
PDBsum8jlb
PubMed37718728
UniProtQ71DI3|H32_HUMAN Histone H3.2 (Gene Name=H3C15)

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