Structure of PDB 8j85 Chain E Binding Site BS01

Receptor Information
>8j85 Chain E (length=399) Species: 128780 (Stenotrophomonas acidaminiphila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVAVQCGRLFDARSGQLKGPHTLLVADGRIRQVLPGARVVDLGDKVCLPG
WTDLHVHLGEQSSPQSYSEDFRLDPVDHAFRAVGYAEKTLMAGFTSVRDL
GGEVSPHLRDAINQGLVRGPRIFAAGKSIATTGGHADPTNGWNERLAHLV
GAPGPAEGVVNSVDEARQAVRQRYKEGSDLIKITATGGVLSYARSGDAPQ
FTVDEIKAVVDTARDYGFRVAAHAHGTEGMKRAVQAGVTSIEHGTYMDDE
VMRLMKQHGTWYVPTFYAGRFVTEKAAIDGYFPEVVRPKAARIGALISQT
AAKAYRNGVRIAFGTNQGVGPHGDNAREFVYMVEAGIPAAYALQAATVHA
AQVLGVDDQGVLEPGKRADVIALAGNPLEDINAVLDVRFVMKDGVIYKQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8j85 Chain E Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8j85 Cryo-EM structure and rational engineering of a superefficient ochratoxin A-detoxifying amidohydrolase.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		H83 H85 K210
Binding residue
(residue number reindexed from 1)		H55 H57 K182
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

View graph for
Molecular Function
External links
PDB RCSB:8j85, PDBe:8j85, PDBj:8j85
PDBsum8j85
PubMed37331057
UniProtA0A0S1B1B6

[Back to BioLiP]