Structure of PDB 8hqy Chain E Binding Site BS01
Receptor Information
>8hqy Chain E (length=95) Species:
9606
(Homo sapiens) [
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HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSA
VMALQEASEAYLVGLFEDTNLSAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>8hqy Chain I (length=136) [
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atgagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatata
Receptor-Ligand Complex Structure
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PDB
8hqy
A Cryptic Basic Groove formed by Ubiquitin and Histone H3 Mediates Selective Recognition of H2AK119Ub Nucleosomes by Synovial Sarcoma X Breakpoint 1 Protein.
Resolution
3.05 Å
Binding residue
(original residue number in PDB)
R63 R72 R83 F84 V117 T118
Binding residue
(residue number reindexed from 1)
R25 R34 R45 F46 V79 T80
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0030527
structural constituent of chromatin
GO:0046982
protein heterodimerization activity
Cellular Component
GO:0000786
nucleosome
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Molecular Function
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Cellular Component
External links
PDB
RCSB:8hqy
,
PDBe:8hqy
,
PDBj:8hqy
PDBsum
8hqy
PubMed
38177667
UniProt
Q71DI3
|H32_HUMAN Histone H3.2 (Gene Name=H3C15)
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