Structure of PDB 8h40 Chain E Binding Site BS01

Receptor Information
>8h40 Chain E (length=620) Species: 1163 (Anabaena) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TNQFDYVKIGLASPERIRQWGERTLPNGQVVGEVTKPETINYRTLKPEMD
GLFCERIFGPAKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGY
IKLAAPVAHVWYLKGIPSYISILLDMPLRDVEQIVYFNSYVVLSPGNAET
LTYKQLLSEDQWLEIEDQIYSEDSQLQGVEVGIGAEALLRLLADINLEQE
AESLREEIGSAKGQKRAKLIKRLRVIDNFIATGSKPEWMVMTVIPVIPPD
LRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRM
LQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVD
YSGRSVIVVGPKLKIHQCGLPREMAIELFQPFVINRLIRSGMVNNIKAAK
KLISRNDPSVWDVLEEVIEGHPVMLNRAPTLHRLGIQAFEPILVEGRAIQ
LHPLVCPAFNADFDGDQMAVHVPLSLESQAEARLLMLASNNILSPATGRP
IITPSQDMVLGAYYLTAENPGATKGAGKYFASLDDVIMAFQQEQIDLHAY
VYVRFDGDVESDQPDTEPVKVTTNEDGSRTVLYKYRRVREDAQGNVISQY
IYTTPGRVIYNKAIQEALAS
Ligand information
>8h40 Chain 1 (length=66) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
attttgtagctacttatacaaaattcaggaaaatttttctgtataatggg
agctgtcacggatgca
Receptor-Ligand Complex Structure
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PDB8h40 Cryo-EM structure of the transcription activation complex NtcA-TAC
Resolution3.6 Å
Binding residue
(original residue number in PDB)		Y47 R48
Binding residue
(residue number reindexed from 1)		Y42 R43
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8h40, PDBe:8h40, PDBj:8h40
PDBsum8h40
PubMed38177666
UniProtP22704|RPOC1_NOSS1 DNA-directed RNA polymerase subunit gamma (Gene Name=rpoC1)

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