Structure of PDB 8gam Chain E Binding Site BS01

Receptor Information
>8gam Chain E (length=283) Species: 486 (Neisseria lactamica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TIEKRYDFVFLFDVQDGNPNGDPDAGNLPRIDPQTGEGLVTDVCLKRKVR
NFIQMTQNDEHHDIFIREKGILNNLIDEAHEQENVKGKEKGEKTEAARQY
MCSRYYDIRTFGAVMTTGKNAGQVRGPVQLTFSRSIDPIMTLEHSITRMA
VTNEKDASETGDNRTMGRKFTVPYGLYRCHGFISTHFAKQTGFSENDLEL
FWQALVNMFDHDHSAARGQMNARGLYVFEHSNNLGDAPADSLFKRIQVVK
KDGVEVVRSFDDYLVSVDDKNLEETKLLRKLGG
Ligand information
>8gam Chain K (length=43) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guugaaacagggucagcuugccguagguggcaucgcccucguc
...........................................
Receptor-Ligand Complex Structure
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PDB8gam Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Resolution3.46 Å
Binding residue
(original residue number in PDB)		N19 N21 G22 P24 G27 N28 V44 C45 R48 R68 G113 A114 Q124 V125 R126 I147 K170 S215 A216 R218
Binding residue
(residue number reindexed from 1)		N18 N20 G21 P23 G26 N27 V43 C44 R47 R67 G112 A113 Q123 V124 R125 I146 K169 S214 A215 R217
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0043571 maintenance of CRISPR repeat elements

View graph for
Biological Process
External links
PDB RCSB:8gam, PDBe:8gam, PDBj:8gam
PDBsum8gam
PubMed38242128
UniProtD0W8X6

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