Structure of PDB 8g8b Chain E Binding Site BS01

Receptor Information
>8g8b Chain E (length=107) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQ
DFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQL
ARRIRGE
Ligand information
>8g8b Chain I (length=168) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atgcacacatgctaatatatgcacacaatgcacacaggttaatatataca
catacacacacatgcacacacacgtgcacacatatatgcacatgcatgca
cacacgtatatgcacacacatgcacatgcatgcgcacatagtcacacaca
tgcacacattagcatatg
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8g8b Histone modifications regulate pioneer transcription factor cooperativity.
Resolution4.3 Å
Binding residue
(original residue number in PDB)		R40 Y41 G44 V46 A47 R49 R63 K64 L65 R69 R83
Binding residue
(residue number reindexed from 1)		R14 Y15 G18 V20 A21 R23 R37 K38 L39 R43 R57
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8g8b, PDBe:8g8b, PDBj:8g8b
PDBsum8g8b
PubMed37225990
UniProtP84233|H32_XENLA Histone H3.2

[Back to BioLiP]