Structure of PDB 8e5t Chain E Binding Site BS01

Receptor Information
>8e5t Chain E (length=143) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKWYPSEDVAALKKTRKAARPQKLRASLVPGTVLILLAGRFRGKRVVYLK
HLEDNTLLISGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFNVEYF
AVEDQKVVDKALIAEIKKTPLLKQYLSASFSLKNGDKPHMLKF
Ligand information
>8e5t Chain 1 (length=743) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaaaagcggaggaaaaga
aaccaaccgggauugccuuaguaacggcgagugaagcggcaaaagcucaa
auuugaaaucugguacggugcccgaguuguaauuuggagagggcaacuug
uaaagugccuucgaagagucgaguuguuuugcagcucuaaguggguggua
aauuccaucuaaagcuaaauauuggcgagagacuuugaaaagagaguaaa
uuguugaaagggaagggcauuugaucagacauggugucacugggccagca
ucaguuuugguggcaggauaaauccauaggaauguagcuugccucgguaa
guauuauagccugugggaauacugccagcugggacugaggacugcgacgu
aagucaaggaugcuggcauaaugguuauaugccgcccgucuugaaacacg
gaccaaggagucuaacgucuaugcgaguguuuggguguaaaacccauacg
cguagguuggggccucgcaagaggugcacaaucgaccgugaguaagagca
uagcuguugggaguuccugccgaaguagaguuaaggugccggaauacacg
cucaucagaggcgcucaagcguguuaccuauacucuaccgucaggguuga
uaugaugcccugacgaguaggcaggcguggaggucagugacgaagccuag
accguaaggucgggucgaacggccucuagugcagaucuuggug
..........................<<<<<<....>>>>>.>...<...
..<<....>>..<<<<<......<<.....>>.....>>>>>..<<<..<
........<<.<<<<<.>>>>>.>>........>....<<<<<<<.<<..
...>>>>>>>>>........<<<<<<<...>>>>>>>.....<<<<<<..
....>>>>>>..>>>....>............<<<<....>>>>......
...............<<<<<.<<<<<<..<..<<<<.>>>>.><<<<<<<
.<<<<<<<<<<<<<<<.....<<<<<<<<<......<<<<<......>>>
>>.......>>>>>>>.>.>.>>>>>.>>>>>>>>>>........<<<..
..>>>.....>>>>>>>....>>>>>>.>>>>>..<<<<........>>>
><<<<<<<...<<<<<<.<<<<<<..<<<<.<<<<<.....>>>>>.>>>
>...<<<<<..<<<<<....>>>>>...>>>>>.<<.....>>....>>>
>>>.>>>>>>..<<.<<<<<<...<<<<<<<..<<<<(((.....<<<<<
<.....<<.))).>>...>>>>>>.>>>>..>>>>>>><<<<<<<<<...
......>>>>>>>>>....>>>>>>..<<<<<<<<.<<......<<<<.<
<<<....>>>>>>>>...>>>>>>>>>>..>>...>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8e5t A co-transcriptional ribosome assembly checkpoint controls nascent large ribosomal subunit maturation.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		A16 A17 L18 K19 T21 R22 K23 A24 R26 Q28 K29 R82 Y83
Binding residue
(residue number reindexed from 1)		A10 A11 L12 K13 T15 R16 K17 A18 R20 Q22 K23 R76 Y77
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8e5t, PDBe:8e5t, PDBj:8e5t
PDBsum8e5t
PubMed37037974
UniProtQ02326|RL6A_YEAST Large ribosomal subunit protein eL6A (Gene Name=RPL6A)

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