Structure of PDB 8cmi Chain E Binding Site BS01
Receptor Information
>8cmi Chain E (length=184) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
MGDTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRA
VTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKV
TVYPSKNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQ
TLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
Ligand information
>8cmi Chain F (length=15) Species:
2697049
(Severe acute respiratory syndrome coronavirus 2) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
TQLKRALTGIAVEQD
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
8cmi
Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
F13 P56 D57 Y60 W61 L67 R71 T77 Y78 H81 N82 V85
Binding residue
(residue number reindexed from 1)
F14 P57 D58 Y61 W62 L68 R72 T78 Y79 H82 N83 V86
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0016020
membrane
GO:0042613
MHC class II protein complex
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:8cmi
,
PDBe:8cmi
,
PDBj:8cmi
PDBsum
8cmi
PubMed
37471227
UniProt
D7RIG0
[
Back to BioLiP
]