Structure of PDB 8auv Chain E Binding Site BS01

Receptor Information
>8auv Chain E (length=136) Species: 4097 (Nicotiana tabacum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTVKDVSPHEFVKAYAAHLKRSGKMELPEWTDIVKTGKLKELAPYDPDWY
YIRAASMARKIYLRGGLGVGGFRRIYGGNQRNGSRPRHFCKSSGSVARNI
LQQLQNMNIVDFDPKGGRRITSNGQRDLDQVAGRIA
Ligand information
>8auv Chain h (length=1626) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcauguguaaguaugaacaaauucagacugugaaacugcgaauggcuc
auuaaaucaguuauaguuuguuugaugguaucuacuacucggauaaccgu
aguaauucuagagcuaauacgugcaacaaaccccgacuucuggaagggau
gcauuuauuagauaugcgaugauucaugauaacucgacggaucgcacggc
cgccggcgacgcaucauucaaauuucugcccuaucaacuuucgaugguag
gauaguggccuaccaugguggugacgggugacggagaauuaggguucgau
uccggagagggagccugagaaacggcuaccacauccaaggaaggcagcag
gcgcgcaaauuacccaauccugacacggggagguagugacaauaaauaac
aauaccggcugguaauuggaaugaguacaaucuaaaucccuuaacgagga
uccauuggagggcaagucuggugccagcagccgcgguaauuccagcucca
auagcguauauuuaaguuguugcaguuaaaaagcucguaguuggacuuug
ggaugucccguuacuuugaagaaauuagagugcucaaagcaagccuacgc
ucuguauacauuagcaugggauaacauuauaggauuucgguccuauuucg
ggaucggaguaaugauuaacagggacagucgggggcauucguauuucaua
gucagaggugaaauucuuggauuuaugaaagacgaacaacugcgaaagca
uuugccaaggauguuuucauuaaucaagaacgaaaguugggggcucgaag
acgaucagauaccguccuagucucaaccauaaacgaugccgaccagggau
cggcggauguugcuaggacuccgccggcaccuuaugagaaaucaaaguuu
uuggguuccggggggaguauggucgcaaggcugaaacuuaaaggaauuga
cggaagggcaccaccaggaguggagccugcggcuuaauuugacucaacac
ggggaaacuuaccagguccagacauaguaaggauugacagacugagagcu
cuuucuugauucuaugggugguggugcauggccguucuuaguugguggag
cgauuugucugguuaauuccguuaacgaacgagaccucagccugcuaacu
agcuaugcggagguaucccuucgcggccagcuucuuagagggacuacggc
cuuuuaggccgcggaaguuugaggcaauaacaggucugugaugcccuuag
auguucugggccgcacgcgcgcuacacugauguauucaacgaguuuauag
ccuuggccgacaggcccggguaaucuuugaaauuucaucgugauggggau
agaucauugcaauuguuggucuucaacgaggaauuccuaguaagcgcgag
ucaucagcucgcguugacuacgucccugcccuuuguacacaccgcccguc
gcuccuaccgauugaaugauccggugaaauguucggaucgcgcgagaagu
ccauugaaccuuaucauuuagaggaaggagaagucguaacaagguuuccg
uaggugaaccugcggaaggaucauug
...<<<<<.[.((((>>>>>.<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<...........>>...>>.>>......<<.
.......<<<..<<..<<....<<<<<............<<.....<..<
<<.....>>>..>......>>........<.<<<..<<...>>..>>>.>
....<<<<<<................>>>>>>.........<<<<.<<<<
.>>>>>>>>..>>>>>...>>>>..>>>.<<<....<<<....<<<<<<<
<.......>>>>>>>>>>>......>>>...<<<.<<<<....>>>>...
.>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>
>>.........<<<....<<<.....>>>..>>>..>....>.>.....<
<<<<<<<..>>>>>.>>>......<<..<...........>..>>.....
....<<<<<((....<.<<<<.....<<..))>>.......>>>>>>>>>
>..>>>>>>>>>..........<.<((.....<.<<...<<<.<<.....
<<<..>>>.<<<<<<.<<.......<<...<.......>..<<<....>>
>.....>>......>>.>>..>>>>........<<<<<<<<<<<.....>
>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<<
<...<<<......>>>......>>>>>>>>..>>.......<<....>>.
..>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<
<<<.........>>>>...>>>>>>>>..........<<<.<<.<<<..<
<<<<<<<.<<<.<..>>>>>>>>>>>>..>>>...<<..))>>...>>..
...>>>.>.>.<<<......<<<<....>>>>....>>>..)))).]<<<
<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<.......<<........>
>..........<<<<<......<<<<<........<<.<<<........>
>>.>>......>>>>>...<<.<<<..<<.<<<<<<....<<<.<<<<..
....>>...<<<......>>>...>>.>>>....<<<<<.<<..<<<<..
<<<<.<<<<<<<<....>>>>>>>>...>>>>..>>>>.>>.....<<<<
<.....>>>>>........>>>>>....>>>.>>>.....>>>>>>>...
....>>>>>....>.>>>>.>>>.....<<<<.<.......<<.......
<<<.<<<<....>>>>.>>>....>>.......>.>>>>......<....
<<<<<<..........>>>>>>....>.....>>>>>>....<<<<<<<<
.......>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<
.<<<<<.<<....<<<<<<<..<<<..<<<<..<...<<<<>>>>...>.
.>>>>..>>>..>>>>>>>...>>.>>>>>..>.>>...>.....<<<<<
<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
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PDB8auv Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution.
Resolution2.38 Å
Binding residue
(original residue number in PDB)
K8 P12 H13 V16 V38 T40 K42 K44 E45 L46 P48 Y49 R57 S60 R63 R68 G70 G72 V73 G74 R78 N83 Q84 R85 G87 S88 R89 P90 R91 H92 F93 S97 S99 R102 Q106 G121 R122 S126 Q129 R130 D133
Binding residue
(residue number reindexed from 1)
K4 P8 H9 V12 V34 T36 K38 K40 E41 L42 P44 Y45 R53 S56 R59 R64 G66 G68 V69 G70 R74 N79 Q80 R81 G83 S84 R85 P86 R87 H88 F89 S93 S95 R98 Q102 G117 R118 S122 Q125 R126 D129
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8auv, PDBe:8auv, PDBj:8auv
PDBsum8auv
PubMed37156858
UniProtA0A1S3Y949

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