Structure of PDB 8aag Chain E Binding Site BS01

Receptor Information
>8aag Chain E (length=97) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
Ligand information
>8aag Chain I (length=185) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
taatattggccagctaggatatcacaatcccggtgccgaggccgctcaat
tggtcgtagacagctctagcaccgcttaaacgcacgtacggaatccgtac
gtgcgtttaagcggtgctagagctgtctacgaccaattgagcggcctcgg
caccgggattgtgatatcctagctggccaatatta
Receptor-Ligand Complex Structure
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PDB8aag Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms.
Resolution10.0 Å
Binding residue
(original residue number in PDB)		H39 R40 Y41 R42 P43 G44 R49 K64 L65 R83
Binding residue
(residue number reindexed from 1)		H2 R3 Y4 R5 P6 G7 R12 K27 L28 R46
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8aag, PDBe:8aag, PDBj:8aag
PDBsum8aag
PubMed36610392
UniProtQ71DI3|H32_HUMAN Histone H3.2 (Gene Name=H3C15)

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