Structure of PDB 7yh5 Chain E Binding Site BS01

Receptor Information
>7yh5 Chain E (length=165) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVVLVDPRRPTLVPVEAIEFLRGEVQYTEEMPVAVPWSLPAARSAHNDA
PVLLSSDPNHPAVITRLAAGARLISAPDSQRGERLVDAVAMMDKLRQTHD
SLRRYLLEETYELLDAVRSGSVDQLREELGDLLLQVLFHARIAEDASQSP
FTIDDVADTLMRKLG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7yh5 Chain E Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7yh5 Structural analysis of the housecleaning nucleoside triphosphate pyrophosphohydrolase MazG from Mycobacterium tuberculosis.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		E119 E138
Binding residue
(residue number reindexed from 1)		E109 E128
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.1.8: ATP diphosphatase.
External links
PDB RCSB:7yh5, PDBe:7yh5, PDBj:7yh5
PDBsum7yh5
PubMed36937295
UniProtP96379|MAZG_MYCTU Nucleoside triphosphate pyrophosphohydrolase (Gene Name=mazG)

[Back to BioLiP]