Structure of PDB 7wm4 Chain E Binding Site BS01

Receptor Information
>7wm4 Chain E (length=661) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQL
AILDAGFNSISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTE
LDLMSNSIHKIKSNPFKNQKNLIKLDLSHNGLSSTKLGTGVQLENLQELL
LAKNKILALRSEELEFLGNSSLRKLDLSSNPLKEFSPGCFQTIGKLFALL
LNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSESTFSGLKWTNLT
QLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRYL
SLKRAFTKSHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKY
LSLSKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQL
RILDLGLNEIEQKLSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQ
RLMLRRVALKNVDISPSPFRPLRNLTILDLSNNNIANINEDLLEGLENLE
ILDFQHNNLARLWNPGGPVNFLKGLSHLHILNLESNGLDEIPVGVFKNLF
ELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVEKDVFGPPFQN
LNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGF
PLKLFDTSSCK
Ligand information
>7wm4 Chain A (length=81) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7wm4 TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		S113 N516 N518 H540 N542
Binding residue
(residue number reindexed from 1)		S85 N482 N484 H506 N508
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7wm4, PDBe:7wm4, PDBj:7wm4
PDBsum7wm4
PubMed36631495
UniProtQ99MB1|TLR3_MOUSE Toll-like receptor 3 (Gene Name=Tlr3)

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