Structure of PDB 7w1e Chain E Binding Site BS01

Receptor Information
>7w1e Chain E (length=644) Species: 1194091 (Klebsiella phage NTUH-K2044-K1-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APERVFSDLASMVAYPNFQVQDKITLLGSAGGDFTFTTTASVVDNGTVFA
VPGGYLLRKFVGPAYSSWFSNWTGIVTFMSAPNRHLVVDTVLQATSVLNI
KSNSTLEFTDTGRILPDAAVARQVLNITGSAPSVFVPLAADAAAGSKVIT
VAAGALSAVKGTYLYLRSNKLCDGGPNTYGVKISQIRKVVGVSTSGGVTS
IRLDKTLHYNYYLSDAAEVGIPTMVENVTLVSPYINEFGYDDLNRFFTIG
ISANFAADLHIQDGVIIGNKRPGASDIEGRSAIKFNNCVDSTVKGTCFYN
IGWYGVEVLGCSEDTEVHDIHAMDVRHAISLNWQSTADGDKWGEPIEFLG
VNCEAYSTTQAGFDTHDIGKRVKFVRCVSYDSAAAGFQARTNGVEYLNCR
AYRAAMDGFASNTGVAFPIYRECLAYDNVRSGFNCSYGGGYVYDCEAHGS
QNGVRINGGRVKGGRYTRNSSSHIFVTKDVAETAQTSLEIDGVSMRYDGT
GRAVYFHGTVGIDPTLVSMSNNDMTGHGLFWALLSGYTVQPTPPRMSRNL
LDDTGIRGVATLVAGEATVNARVRGNFGSVANSFKWVSEVKLTRLTFPSS
AGALTVTSVAQNQDVPTPNPDLNSFVIRSSNAADVSQVAWEVYL
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain7w1e Chain M Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7w1e Structural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use.
Resolution1.46 Å
Binding residue
(original residue number in PDB)		K177 N217
Binding residue
(residue number reindexed from 1)		K170 N210
Annotation score4
Enzymatic activity
Enzyme Commision number 4.-.-.-
Gene Ontology
Biological Process
GO:0046718 symbiont entry into host cell
GO:0098671 adhesion receptor-mediated virion attachment to host cell
GO:0098994 symbiont entry into host cell via disruption of host cell envelope
GO:0098996 symbiont entry into host cell via disruption of host cell glycocalyx
Cellular Component
GO:0098015 virus tail

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7w1e, PDBe:7w1e, PDBj:7w1e
PDBsum7w1e
PubMed35130876
UniProtA0A068Q5Q5|DEPOL_BPKNT Depolymerase, capsule K1-specific (Gene Name=ORF34)

[Back to BioLiP]