Structure of PDB 7w0s Chain E Binding Site BS01

Receptor Information
>7w0s Chain E (length=169) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGF
SSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQY
WAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQE
RVFPLFSVCSTGTYLRIWP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7w0s A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Resolution1.4 Å
Binding residue
(original residue number in PDB)
T382 N383 T384 R385 A410 L423 F426 Q436 S499 C501
Binding residue
(residue number reindexed from 1)
T40 N41 T42 R43 A68 L81 F84 Q94 S157 C159
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:7w0s, PDBe:7w0s, PDBj:7w0s
PDBsum7w0s
PubMed35982226
UniProtQ9C029|TRIM7_HUMAN E3 ubiquitin-protein ligase TRIM7 (Gene Name=TRIM7)

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