Structure of PDB 7umi Chain E Binding Site BS01

Receptor Information

>7umi Chain E (length=424) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKF
VSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASP
HAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACG
YLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWA
ISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGT
DEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVV
NHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEP
LMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIE
ALQRHENESVYKASLNLIEKYFSV

Ligand information

>7umi Chain A (length=10) Species: 10407 (Hepatitis B virus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

SQSPRRRRSQ

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7umi Nuclear import of Hepatitis B Virus
Resolution	1.99 Å
Binding residue (original residue number in PDB)	S105 R106 E107 P110 W142 N146 A148 S149 G150 Q181 W184 N188 D192 W231 R238 D270 W273
Binding residue (residue number reindexed from 1)	S31 R32 E33 P36 W68 N72 A74 S75 G76 Q107 W110 N114 D118 W157 R164 D196 W199

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0061608	nuclear import signal receptor activity

	Biological Process
GO:0006606	protein import into nucleus

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7umi, PDBe:7umi, PDBj:7umi
PDBsum	7umi
PubMed	38198557
UniProt	P52293\|IMA1_MOUSE Importin subunit alpha-1 (Gene Name=Kpna2)

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