Structure of PDB 7ttr Chain E Binding Site BS01

Receptor Information

>7ttr Chain E (length=332) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RKREAEERRRFPLEQRLKEHIIGQESAIATVGAAIRRKENGWYDEEHPLV
FLFLGSSGIGKTELAKQTAKYMHKDAKKGFIRLDMSEFQERHEVAKFIGS
PPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRL
TDGKGKTIDCKDAIFIMTSNVASDEIAQHALQLRQEALEMSITISKNFKE
NVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWAKRAK
QRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDL
LPGGCTLRITVEDSDKQLLKSPELPSPQAEKR

Ligand information

>7ttr Chain P (length=14) Species: 9913 (Bos taurus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

AAAAAAAAAAAAAA

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7ttr Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3.
Resolution	2.96 Å
Binding residue (original residue number in PDB)	G429 Y430 V431
Binding residue (residue number reindexed from 1)	G103 Y104 V105

Enzymatic activity

Enzyme Commision number

3.6.1.-

Gene Ontology

	Molecular Function
GO:0005524	ATP binding
GO:0016887	ATP hydrolysis activity

View graph for
Molecular Function

External links

PDB	RCSB:7ttr, PDBe:7ttr, PDBj:7ttr
PDBsum	7ttr
PubMed	36170828
UniProt	Q9H078\|CLPB_HUMAN Mitochondrial disaggregase (Gene Name=CLPB)

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