Structure of PDB 7tm9 Chain E Binding Site BS01

Receptor Information
>7tm9 Chain E (length=441) Species: 1125630 (Klebsiella pneumoniae subsp. pneumoniae HS11286) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NRAAQGDITTPGGARRLTGDQTEALRASLINKPAKNVILLIGDGMGDSEI
TAARNYAEGAGGFFKGIDALPLTGQYTHYSLDKKTGKPDYVTDSAASATA
WTTGVKTYNGALGVDIHENAHQTILELAKAAGLATGNVSTAELQDATPAA
LVAHVTSRKCYGPTVTSEKCPSNALEKGGKGSITEQLLNARPDVTLGGGA
KTFAETATAGEWQGKTLREQAQARGYQIVTDAASLAAATEASQDKPLLGL
FADGNMPVRWEGPKASYHGNIDKPPVTCTPNPKRDASVPTLAQMTEKAID
LLSRNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQKALEFARK
DGNTLVIVTADHAHASQIIPADSKAPGLTQALNTHDGAVMVMSYGNSEEE
SMEHTGTQLRIAAYGPHAANVVGLTDQTDLFTTMKAALSLK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7tm9 Chain E Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7tm9 Crystal structure of Bacterial alkaline phosphatase from Klebsiella pneumoniae
Resolution1.95 Å
Binding residue
(original residue number in PDB)		S117 D342 H346 H427
Binding residue
(residue number reindexed from 1)		S94 D319 H323 H404
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016791 phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:7tm9, PDBe:7tm9, PDBj:7tm9
PDBsum7tm9
PubMed
UniProtA0A0H3GK94

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