Structure of PDB 7t2c Chain E Binding Site BS01

Receptor Information
>7t2c Chain E (length=248) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVVSQHPSWVICKSGTSVKIECRSLDFQATTMFWYRQFPKQSLMLMATSN
EGSKATYEQGVEKDKFLINHASLTLSTLTVTSAHPEDSSFYICSARDPGG
GGSSYEQYFGPGTRLTVTEDLNKVFPPEVAVFEPSEAEISHTQKATLVCL
ATGFFPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRV
SATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD
Ligand information
>7t2c Chain C (length=12) Species: 1313 (Streptococcus pneumoniae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TGLAWEWWRTVY
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7t2c CD4 + T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
P109 G110
Binding residue
(residue number reindexed from 1)
P98 G99
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7t2c, PDBe:7t2c, PDBj:7t2c
PDBsum7t2c
PubMed37100059
UniProtP01850|TRBC1_HUMAN T cell receptor beta constant 1 (Gene Name=TRBC1)

[Back to BioLiP]