Structure of PDB 7s78 Chain E Binding Site BS01

Receptor Information
>7s78 Chain E (length=926) Species: 28285 (Human adenovirus 5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPTHD
VTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDIRG
VLDRGPTFKPYSGTAYNALAPKGAPNPCEWDEAATALQQKTHVFGQAPYS
GINITKEGIQIGVEGQTPKYADKTFQPEPQIGESQWYETEINHAAGRVLK
KTTPMKPCYGSYAKPTNENGGQGILVKQQNGKLESQVEMQFFSTTEATAG
NGDNLTPKVVLYSEDVDIETPDTHISYMPTIKEGNSRELMGQQSMPNRPN
YIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLD
SIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGVINTET
LTKVKPKTGQENGWEKDATEFSDKNEIRVGNNFAMEINLNANLWRNFLYS
NIALYLPDKLKYSPSNVKISDNPNTYDYMNKRVVAPGLVDCYINLGARWS
LDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLL
PGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPMAHN
TASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNWAAF
RGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVAITF
DSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYN
IGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGILHQHNN
SGFVGYLAPTMREGQAYPANFPYPLIGKTAVDSITQKKFLCDRTLWRIPF
SSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDV
VRVHRPHRGVIETVYLRTPFSAGNAT
Ligand information
>7s78 Chain 0 (length=16) Species: 28285 (Human adenovirus 5) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NFASLAPRHTSNMSGG
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7s78 Structure of a Cell Entry Defective Human Adenovirus Provides Insights into Precursor Proteins and Capsid Maturation.
Resolution3.72 Å
Binding residue
(original residue number in PDB)		Q29 F30 A33 T34 T36 R45 N46
Binding residue
(residue number reindexed from 1)		Q25 F26 A29 T30 T32 R41 N42
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus
Cellular Component
GO:0019028 viral capsid
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7s78, PDBe:7s78, PDBj:7s78
PDBsum7s78
PubMed34774568
UniProtP04133|CAPSH_ADE05 Hexon protein (Gene Name=L3)

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