Structure of PDB 7rlk Chain E Binding Site BS01

Receptor Information
>7rlk Chain E (length=115) Species: 9315 (Notamacropus eugenii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CPLMVKVLDAVRGRPAVNVDVKVFKKTEEQTWELFAAGKTNDNGEIHELT
TDDKFGEGLYKVEFDTISYWKALGVSPFHEYADVVFTANDAGHRHYTIAA
LLSPYSFSTTAIVSN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7rlk Chain E Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7rlk Structural and amyloidogenic comparisons of human and wallaby transthyretins: implications for amyloidosis?
Resolution2.69 Å
Binding residue
(original residue number in PDB)		D61 H102 H104
Binding residue
(residue number reindexed from 1)		D52 H93 H95
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
GO:0070324 thyroid hormone binding
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0007165 signal transduction
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rlk, PDBe:7rlk, PDBj:7rlk
PDBsum7rlk
PubMed
UniProtP42204|TTHY_NOTEU Transthyretin (Gene Name=TTR)

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