Structure of PDB 7rjd Chain E Binding Site BS01

Receptor Information
>7rjd Chain E (length=137) Species: 237561 (Candida albicans SC5314) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FLSSFAASADVLAMAKVEVKLGAIPEGKNVIIKWQGKPVFIRHRTADEIE
EANQVDIKTLRDPQNDADRVKKPEWLIMLGICTHLGCVPIGEAGDFGGWF
CPCHGSHYDISGRIRKGPAPLNLEIPEYDFTDDETLL
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7rjd Chain E Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7rjd Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		T157 L159 G160 C161 C177 H178
Binding residue
(residue number reindexed from 1)		T83 L85 G86 C87 C103 H104
Annotation score1
Enzymatic activity
Enzyme Commision number 7.1.1.8: quinol--cytochrome-c reductase.
Gene Ontology
Molecular Function
GO:0008121 ubiquinol-cytochrome-c reductase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
GO:0006412 translation
GO:0009060 aerobic respiration
GO:0045333 cellular respiration
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0045275 respiratory chain complex III

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rjd, PDBe:7rjd, PDBj:7rjd
PDBsum7rjd
PubMed34525326
UniProtA0A1D8PJX3|RIP1_CANAL Cytochrome b-c1 complex subunit Rieske, mitochondrial (Gene Name=RIP1)

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