Structure of PDB 7re5 Chain E Binding Site BS01

Receptor Information
>7re5 Chain E (length=107) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMCSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLEVCDDY
SLDDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDE
IYLESCC
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7re5 Chain E Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7re5 Pentameric assembly of the Kv2.1 tetramerization domain.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H105 C132 C133
Binding residue
(residue number reindexed from 1)		H79 C106 C107
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005249 voltage-gated potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0051260 protein homooligomerization
Cellular Component
GO:0008076 voltage-gated potassium channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7re5, PDBe:7re5, PDBj:7re5
PDBsum7re5
PubMed35647925
UniProtQ14721|KCNB1_HUMAN Potassium voltage-gated channel subfamily B member 1 (Gene Name=KCNB1)

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