Structure of PDB 7p49 Chain E Binding Site BS01

Receptor Information
>7p49 Chain E (length=266) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYT
CHVQHEGLPEPVTLRW
Ligand information
>7p49 Chain R (length=9) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RMAATAQVL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7p49 Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
Resolution2.05 Å
Binding residue
(original residue number in PDB)		Y7 R62 E63 S66 A67 I73 N77 Y84 E114 F116 S143 K146 E152 H155 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 R62 E63 S66 A67 I73 N77 Y84 E114 F116 S143 K146 E152 H155 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7p49, PDBe:7p49, PDBj:7p49
PDBsum7p49
PubMed35705051
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

[Back to BioLiP]