Structure of PDB 7ouf Chain E Binding Site BS01

Receptor Information
>7ouf Chain E (length=278) Species: 33747 (Simian T-lymphotropic virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPAKLHSFTHCGQAALTLHGATTTEALNILHSCHACRKNNPQHQMPRGHI
RRGLLPNHIWQGDITHFKYKNTLYRLHVWVDTFSGSVSATHKKRETSSEA
ISSLLHAIAHLGRPSHINTDNGPAYASQEFQHACTSLAIRHTTHIPYNPT
SSGLVERTNGILKTLLYKYFSDNPNLPMDNALSVALWTINHLNVLTHCQK
TRWQLHHSPRLPPIPEEKPVTTSKTHWYYFKIPGLNSRQWKGPQRALQEA
AGAALIPVSDTAAQWIPWKLLKRAVCPR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7ouf Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		G50 H51 I52 R53 R54 T144 H146 I147 N150 T152 S153 G155 L156 R159 T198 R204 Q250 A252 A253 W267 K271
Binding residue
(residue number reindexed from 1)		G48 H49 I50 R51 R52 T142 H144 I145 N148 T150 S151 G153 L154 R157 T196 R202 Q248 A250 A251 W265 K269
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7ouf, PDBe:7ouf, PDBj:7ouf
PDBsum7ouf
PubMed34404793
UniProtQ4QY51

[Back to BioLiP]