Structure of PDB 7m65 Chain E Binding Site BS01

Receptor Information
>7m65 Chain E (length=32) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TCATQRLANFLVHSSNNFGAILSSTNVGSNTY
Ligand information
>7m65 Chain F (length=23) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NFLVHSSNNFGAILSSTNVGSNT
Receptor-Ligand Complex Structure
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PDB7m65 Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores
Resolution4.1 Å
Binding residue
(original residue number in PDB)		T36 Y37
Binding residue
(residue number reindexed from 1)		T31 Y32
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:7m65, PDBe:7m65, PDBj:7m65
PDBsum7m65
PubMed
UniProtP10997|IAPP_HUMAN Islet amyloid polypeptide (Gene Name=IAPP)

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